• Nội sảnh 221B phố Baker được bài trí theo tường thuật của tác giả Arthur Conan Doyle, đặc sệt phong cách Victoria, có hình nộm các nhân vật chính cùng một số nhân vật phụ tương ứng các vụ hay nhất của Holmes[3][4][5].
• Số 221B phố Baker ngày nay được xếp vào địa chỉ đỏ trong du lịch trình London[6].
• Scotland Yard luân phiên cử một sĩ quan đứng trực trước cửa địa chỉ này.

The fictional address has been portrayed in the following pastiches of Sherlock Holmes:

• Basil of Baker Street resides in 221½ Baker Street, a mouse-hole beneath 221B Baker Street.[7]
• Private detective Louie Knight moves into an office at 22/1B Stryd-y-Popty (which translates as Baker Street in Welsh) in Malcolm Pryce's Welsh Noir parody The Unbearable Lightness of Being in Aberystwyth.
• The 1987 CBS movie The Return of Sherlock Holmes (not to be confused with the 1986 British television series of the same name) features Holmes, cryogenically frozen in 1899 and awakened in modern times, trying to adapt with the aid of Watson's granddaughter, Jane. He seeks out his old residence and finds the spot occupied by a McDonald's franchise.[8]
• Dr. Gregory House, the protagonist of House, M.D., lives at 221 Baker Street, Apartment B, Princeton, NJ, 08542.[9]
• Danger Mouse, in the cartoon show of the same name, lives in a pillar box near 221b Baker Street.[10] However, Danger Mouse is a loose parody of Danger Man and James Bond, rather than Sherlock Holmes. The pillar box is a stone's throw away from 221B Baker Street and Dr. Watson throws stones at them in apparent jealousy that he only works for the world's greatest detective, not the world's greatest secret agent in the episode "Where There's a Well, There's a Way".
• In the Phryne Fisher series by Kerry Greenwood, the detective Hon. Phryne Fisher resides at 221 The Esplanade, St Kilda (Melbourne, Australia), which she renumbers to 221B in homage to Holmes.[11]
• In Star Trek: The Next Generation, Data tells another crew member that Geordi La Forge can be found at 221b Baker St, episode 29 "Elementary, Dear Data", and 221b Baker St. is again referenced in episode 137 "Ship in a Bottle".[12]
• In Season 2, Episode 1 of Elementary, Sherlock Holmes and Joan Watson visit London and stay in a second floor residence numbered 221B. Sherlock indicates he had happily resided there before his move to New York City.[13]
• In the 2015 film Mr. Holmes, a long-retired Holmes (Ian McKellen) remarks that the Baker Street address is one of several fictitious details created by Watson, who wrote the cases up as sensationalist stories for publication. In a flashback, as curious onlookers gather outside 221B, Holmes watches from a window of his actual residence nearby and congratulates a client for finding the right address.[14]
• The BBC Television series Sherlock has used 187 North Gower Street to represent 221B Baker Street for shooting the exterior scenes of Sherlock Holmes' flat. The location is near Euston railway station, and roughly a mile away from the real Baker Street.[15]
• In the 2012-15 Australian television series Miss Fisher's Murder Mysteries, the title character of The Honourable Phryne Fisher (Essie Davis) lives at 221B Baker Street in Melbourne, Victoria.[16]